Integrated Geomechanical Characterization of Anisotropic Gas Shales: Field Appraisal, Laboratory Testing, Viscoelastic Modelling,and Hydraulic Fracture Simulation

This research provides a multiscale geomechanical characterization workflow for ultra-tight and anisotropic Goldwyer gas shales by integrating field appraisal, laboratory deformation and ultrasonic testing, viscoelastic modelling, and hydraulic fracture simulation. The outcome of this work addresses few of the practical challenges in unconventional reservoirs including but not limited to (i) microstructure & compositional control on rock mechanical properties, (ii) robust estimation of elastic anisotropy, (iii) viscous stress relaxation to predict the least principal stress Shmin at depth from creep, (iv) influence of specific surface area on creep, and (v) impact of stress layering on hydraulic fracturing design

PUO with multiple abscesses due to Burkholderia pseudomallei: a case report

Melioidosis is an infectious disease of humans and animals caused by Burkholderia pseudomallei, previously called as Pseudomonas pseudomallei. We reported a case of a 14 year old female patient presented with fever for last 3 months and multiple swellings of joints, misdiagnosed as M.D.R. T.B. But after proper evaluation diagnosed as multiple joint abscess due to Pseudomonas pseudomallei mimiking tuberculosis. Sporadic cases of melioidosis from various parts of South Indiaand Western costal India have been reported, but remained underdiagnosed due to lack of awareness

Evaluation of mosquito larvicidal activity of Azolla pinnata leaf extracts against the filarial vector Culex quinquefasciatus

52-59Vector control is a major challenge now-a-days when they became resistance against commonly available insecticides. As an alternative, preliminary laboratory evaluation of Azolla pinnata crude and chloroform: methanol solvent extract was carried out under laboratory trials for control of Culex quinquefasciatus. Crude and solvent extract (chloroform: methanol) extracts of A. pinnata leaves were examined for the larvicidal activity against all the larval instars (1st to 4th) of C. quinquefasciatus. Dose-dependent mortality assays were performed using the extracts. Further, determinations of LC50 and LC95 values were accomplished through log-probit analyses and regression analyses. The larvicidal activity was statistically justified through ANOVA analyses. Effects of the extracts were examined on non-target water fauna. Exposure to A. pinnata crude and chloroform: methanol extract increased the mortality of first to fourth-instar C. quinquefasciatus. All the graded concentrations showed significant (P <0.05) larval mortality and the results of the regression equation revealed that the mortality rates were positively correlated with the concentrations of the extracts (R2 close to 1). LC50 values of all instars after 24 h of exposure were between 86.99-294.06 ppm for crude and 48.87-111.44 ppm for chloroform: methanol extract. Chloroform: methanol extract is better than crude because the nature of biological components can be enhanced in presence of solvent and secondly the stronger extraction capacity could have produced a greater number of active constituents. The residual effect is noted even at the end of 72 h. A negligible toxicity to the larvae of Chironomus circumdatus was noticed as non-target organisms

Chronic airway obstruction in post tubercular fibrosis cases:a serious lung function changes

Background: Tuberculosis (TB) is a major cause of death worldwide. About two thirds of patients develop impaired pulmonary function after completion of pulmonary tuberculosis treatment. But data is lacking to support this assertion. Objective of the study was to determine the frequency of chronic obstructive pulmonary disease (COPD) in post tubercular fibrosis patients in the hospital.Methods: This is a cross-sectional study which was done at Medinipore Medical College & Hospital in post tubercular fibrosis patients from August 2015 to July 2016. 72 patients who had post tubercular fibrosis were included for spirometry test. Those having a probability of re-activated TB, having history of current or previous smoking or occupational exposure, asthmatics and cases of interstitial lung disease and ischemic heart disease were excluded. Pre- and post-dilator FVC, FEV1 and FEV1/FVC were recorded in each case through simple spirometry.Results: There were 83.3% (n=72) males. Thirty eight (52.7%) were found to have an obstructive ventilatory defect of different degrees: severe/stage III in 63.1% (n=24), moderate/stage II in 21.5%% (n=8) and mild/stage I in 15.7 % (n=6). Ten (13.8) were found to have a restrictive pattern and 12 (16.6%) revealed a mixed obstructive and restrictive pattern. Only 12 patients (16.6%) had normal lung function. Among the 38 patients with obstruction in spirometry, 24 patients (63.2%) were under weight.Conclusions: Chronic obstructive pulmonary disease can occur as one of the chronic complications of pulmonary tuberculosis and the obstructive ventilatory defect appears more common especially in patients with low BMI

Miller Fisher Variant of Guillain-Barré Syndrome: A Case Report & Clinical Review

Miller Fisher syndrome (MFS) is an uncommon variant of Guillain-Barré syndrome (GBS). It is characterized by external ophthalmoplegia, ataxia, and areflexia. The incidence of MFS as a proportion of GBS was reported to be 1 to 5 % in western countries and considerably higher in Eastern Asia i.e. 19% in Taiwan and 25% in Japan. Here we report the clinical features of a patient who initially presented with ataxia then subsequently developed limb weakness, areflexia and ophthalmoplegia. CSF study and NCV study supported our clinical diagnosis. Patient was managed conservatively. No intravenous immunoglobulin was given but the patient gradually improved in symptoms including power, ataxia, ophthalmoparesis. After one month the patient was discharged from hospital with complete recovery.DOI: http://dx.doi.org/10.3329/bsmmuj.v5i1.11028 BSMMU J 2012; 5(1):69-71

Strategies to control invasion of Sailfin Armoured Catfish, Pterygoplichthys spp. in wastewater-fed aquaculture bheries of East Kolkata Wetland, India with suggestion of a modified barrier based on the biological and behavioural characteristics

Sailfin armoured catfish (Pterygoplichthys spp.), an alien invasive species of family Loricariidae has invaded extensively in wastewater-fed large aquaculture ponds (locally called ‘bheries’) of East Kolkata Wetlands (EKW), West Bengal, India. As there is no viable controlling method at present, commonly these fishes are removed by different physical methods and discarded. In the present study, we investigated the effectiveness and suitability of different in-practice Pterygoplichthys spp. control methods, based on on-field sampling, biological and behavioural study of the fish and also response analysis of the stakeholder’s of EKW. The results indicate that in-practice eradication efforts, like ‘repeated seine netting’ with or without removal of Eichhornia sheath of the pond periphery and ‘dewatering of pond’ aiming to reduce or eradicate Pterygoplichthys spp., are not fully effective, because of the capture avoidance ability and burrowing habit of these fishes. We found deep and branching burrows of Pterygoplichthys spp. in aquaculture ponds of EKW, with maximum burrow depth of 58 cm, and water in that burrows even after 12 days of dewatering. Hence, it is suggested stakeholders to keep dewatered pond exposed to sunlight for at least four weeks or above to ensure complete water-out from the burrows in which Pterygoplichthys spp. take shelter or lay their eggs. ‘Multilayer bamboo fencing’ or ‘combination of bamboo fencing and net barrier’ use by the stakeholders of EKW to prevent intrusion or re-intrusion of Pterygoplichthys spp. were found only partially effective, because of the capability of these fishes to damage net-blocking through their hard dorsal and pectoral spines or entry through the holes dug across the barrier in beneath or banks of the sewage intake channel. Based on learning on the biological and behavioural characteristics of Pterygoplichthys spp., we then suggested a modified version of barrier to the stakeholder’s of EKW, incorporating a sewage feeder pipeline, a concrete collection chamber with size separation arrangement made of hard materials like wire mesh and a dam of specific dimensions across the channel, for effective prevention of intrusion of these fishes in their aquaculture bheries

A RETROSPECTIVE STUDY ON THE INCIDENCE OF FISH DISEASES AND USE OF THERAPEUTANTS IN AQUACULTURE FARMS OF MOYNA, THE ‘FISHERIES HUB’ OF WEST BENGAL, INDIA

The present study depicts the disease incidences in the aqua farms of Moyna, West Bengal, India, during 2018- 2020 and aqua-drugs used by farmers to combat diseases. A total of 132 fish disease incidences were reported, among which parasitic diseases were the most common (53.03%) followed by bacterial diseases (27.27%), diseases due to poor nutrition and environmental fluctuations (10.61%), and fungal diseases (9.09%), respectively. Out of the 53.03% parasitic disease incidences reported, Argulus (22.86%), Dactylogyrus (17.14%), Gyrodactylus (10.00%), Myxospores (10.00%), Lernaea (8.57%), Ichthyophthirius (5.71%) and Trichodina (4.29%) were the major disease-causing parasites. Among bacteria, Pseudomonas spp. and Aeromonas spp. were the most dominant genera encountered in diseased fish. Labeo catla was the most susceptible fish species followed by Labeo rohita, and Cirrhinus mrigala. Seasonal influence in disease occurrence was noticed. Monsoon and winter were favorable seasons for disease outbreaks. The influence of water quality parameters like hardness, pH, ammonia, total dissolved solids of water, and total organic carbon of sediment had a significant correlation with parasite abundance. Farmers of Moyna were observed to use a wide range of chemicals and aqua-drugs to control diseases and related problems. The majority of the fish farms of Moyna were found using feed additives and supplements (32.00%) followed by sanitizers and disinfectants (24.00%), probiotics (17.00%), anti-parasitic drugs (11.00%), antibiotics (8.00%), and other chemicals (20.00%). Lime (calcium carbonate) and zeolite along with sodium chloride, potassium permanganate, formalin, and calcium hypochlorite were extensively used as disinfectants in Moyna. Farmers being unaware of the adverse consequences of using chemicals and aqua-medicines are fully dependent on private aquaculture consultants for time-to-time advice, which may have augmented their indiscriminate use. Initiative for the implementation of better management practices by creating awareness among farmers and adopting strict aquaculture policy guidelines might improve the scenario

A textbook of homoepathic pharmacy

In this edition some important additions have been made in the text of original chapters such as 'Pharmacopoeia and Pharmacy', 'Brief Study of Standardisation of Drugs and Medicines', 'Quality Control in Homoeopathic Pharmacy', 'The Technique of Homoeopathic Drug Proving', 'Dispensing of Medicines', 'Drug Administration', 'Drug-Medicine-Remedy', 'General Knowledge of Legislation in relation to Homoeopathic Pharmacy'. A 'Glossary' has been given at the end of this book for easy explanation of terms related to homoeopathic pharmacy. This edition will be helpful to students, doctors, pharmacists and research workers in homoeopathy

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